The angels told Lot that God was going to destroy Sodom and Gomorrah because of their wickedness, and asked him to get his family together so that they could escape from the place. Lot had two daughters who were to marry two men in that city, and so Lot went out and told them to come away with him. But they didn't take it seriously but only laughed at him.

Early in the morning, the angels told Lot, his wife and two daughters to run away from the place as fast as they could towards the mountains and not even to look back. When Lot hesitated, these angels caught hold of their hands and forcibly pulled them outside the city out of concern for their safety. As they went, Lot's wife could not resist taking another look at their house and what they had left behind, even though God had told them not to do it. She immediately turned into a pillar of salt. Lot and the daughters went up the mountain into a cave.

God destroyed these cities of Sodom and Gomorrah by raining fire and burning sulphur on them. Everything was burned to ashes, and it is believed that the present Dead Sea is located in that same area.

The two daughters were shocked at what had happened, and staying in that remote cave without anyone near them they feared that they might never be able to get married. So they schemed together between them and decided to become pregnant from their father. They made Lot drunk with wine on two consecutive nights and slept with him. They did become pregnant, and gave birth to sons called Moab and Ben-ammin. These two boys later became the ancestors of two nations of people called the Moabites and the Ammonites.

This is what happened to Lot after he chose to go after wealth and prosperity at the risk of getting wrongly influenced by the immoral people of Sodom and Gomorrah. He lost his wife finally, and he had to see his two daughters grow up without any sense of morality and falling into incest.